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And it's time right now for Sunday house call joining us this morning doctor Marc Siegel associate professor of medicine -- -- when got a medical center and the author of the inner pulse unlocking the secret code of sickness and health.
Doctor Davidson money he's the vice chairman of the department of urology and she's robotics at the Mount Sinai Medical Center here -- New York doctor is always good.
To see you know we're gonna be -- morning good morning morning I'm particularly excited about this first topic that you brought us because so many people know someone who has alzheimer's that they really loving care about him for the very first time.
Researchers have discovered a gene that may actually protect folks against the degenerative brain disease.
Doctor -- this is exciting isn't it.
It's so important because we fought for a really long time that a protein called beta amyloid.
Which builds up in the brain of people with alzheimer's patients remember that word a beta amyloid it clogs the nerves.
And as you said Jamie this is something that is really prominent this disease five million people in the United States have it probably more undiagnosed.
But beta amyloid by the time you see that in the brain it's really too late to do anything there's another enzyme called amyloid precursor protein.
Eight PP that's what causes the amyloid to form.
A study out of Iceland though just found that if you have a mutation a change.
To that particular protein you don't make the amyloid and guess what you have all over a seven times less chance of getting -- congress seven times -- and they -- -- -- over a thousand people and it was very convincing so for all of the new drugs out there.
Targeted therapy antibiotics that are targeting this amyloid.
There's a lot of six assessed possibly on the horizon we're looking at now how you block the -- how you get the same thing as in this rare.
Segment of the population it's very rare that you have this -- We asked are just some -- that sounds good to me I wanna start on it right now -- it is Canada can you do anything right now.
Well of this.
You look at someone who's eighty year old and is actually functional is doing well and is still working and another eighty year old person.
This complete non functional why does that happen.
And I think this goes back to what mark which is trying to say there are some genetic differences between all of us and that's what we're seeing.
We talk about -- what is exactly -- the -- plaque that sits in the arteries and causes a heart attack.
-- on -- plaque can go to the brain it's a different type but it's the same concept.
And they formation from one side of the brain doesn't get to the other side so what does that do.
Outsider and that's what we have to do most of the studies and the big news here in how Simon is we're making it very small step forward in this field.
That has robbed the -- brain of the population five million people so how do we do this either we have to prevent the platform forming right Jamie -- Wash it out when it's formed I think that's what the definition is here to antibodies can clean it up and this is really had the research level we have still a long way to go.
As you -- it's a very devastating problem when we see it on a human level.
A lot of people that we'll get there actresses are coming back I was just awful so now but the big news that's not part of this article we talked about -- -- that that imaging part of this these new pet scans.
And in new images are able to detect these plaques much -- of the year and perhaps you can do something.
I guess in the past we've talked about the vitamin B twelve.
If you don't have outside marry you may have -- deficiency of vitamin B twelve.
That's easy way to really check it but there's a fine of humans have so he should write that check it check vitamin B twelve right now -- -- -- dot.
Oh absolutely David it's great that he's bringing -- up and brings up another point which is alchemy mapping out times if you have dementia you could be depressed you could ever be twelve deficiency.
You can have many strokes there's many other things -- before someone puts that disease on -- that name.
Get a check by position.
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